Change language Go to Italian Version


>List all the bibliography
On the (un)effectiveness of proton boron capture in proton therapy
Authors A. Mazzone, P. Finocchiaro, S. Lo Meo, N. Colonna  Year 2019
Pubblication type Paper International Journal with referee
Abstract We present calculations and simulations on the role of the p+11B→3α reaction in proton therapy. This reaction has been recently suggested to be responsible for a decrease in the survival probability of tumor cells, when they are irradiated with low-energy protons. However, at the concentration levels typical of the proposed boron carrier (sodium borocaptate, Na2B12H11SH, in short BSH), i.e. less than 100 ppm, both calculations and Monte Carlo simulations suggest that the dose related to this reaction is orders of magnitude lower than the dose delivered by the primary proton beam inside the tissues. These calculations cast some doubts on the claim of an important role played by Proton Boron Capture in enhancing the therapeutic effectiveness of proton therapy, and suggest that other mechanisms should be investigated in order to explain the observed decrease in the survival probability.
Reference Eur. Phys. J. Plus 134 (2019) 361
WEB Reference
WEB Reference 2
Research unit RADEC
LastUpdate 05/01/2022
Related research topics
Code Topic Description

impact factor Vero

back to Home page






logo rete alta tecnologia emilia romagna

Il Laboratorio ha realizzato progetti finanziati dai Fondi europei della Regione Emilia-Romagna e dal Fondo per lo sviluppo e la coesione
Termini di uso
Politica sulla Privacy

Share this page with

LinkedIN share Facebook share share
Dichiarazione di accessibilità 6d66ae69-c6fd-4cb9-b536-be3fdfb0144c